BDBM50220388 3'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL443579

SMILES COc1cccc(c1)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=WZNDOEVWUZFICK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220388   

TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220388(3'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50:  9.46E+3nMAssay Description:Binding affinity at human PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220388(3'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50:  955nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220388(3'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed