BDBM50220581 7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-1-hydroxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL246635

SMILES CC(C(O)c1ccc2NC(=O)COc2c1)N1CCC(O)(CC1)c1ccc(F)cc1

InChI Key InChIKey=KMTMWUFYNBUHOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220581   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50:  8.70nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed