BDBM50220703 (R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((1-methyl-1H-tetrazol-5-yl)methyl)piperidin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL250508

SMILES Cn1nnnc1CC1(CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1

InChI Key InChIKey=IJYUZXAPJHBRJR-WDYNHAJCSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50220703   

TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220703((R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  115nMAssay Description:Antagonist activity at human MC3R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220703((R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50:  0.850nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220703((R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  222nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220703((R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  3.20nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed