BDBM50220961 1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl]-ethanone::CHEMBL250743

SMILES CC(=O)C1=NN2[C@@H](COc3ccc(F)cc23)[C@@]1(CCCO)c1ccccc1

InChI Key InChIKey=DVLXDPTZHLUZHB-PZJWPPBQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220961   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220961(1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220961(1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed