BDBM50221224 1-(1-(3-(4-(6-fluorobenzo[b]thiophen-3-yl)piperidin-1-yl)-2-hydroxypropyl)-3-(4-(trifluoromethyl)phenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone::CHEMBL237544

SMILES CC(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)c1csc2cc(F)ccc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UUGWWDUNCOPXGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221224   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221224(1-(1-(3-(4-(6-fluorobenzo[b]thiophen-3-yl)piperidi...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed