BDBM50223567 3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL401303::US8580782, 8

SMILES Clc1ccccc1-c1cc(NCc2cccnc2)n2ncc(Br)c2n1

InChI Key InChIKey=KVSIJRIBZQPYQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223567   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223567(3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)p...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50223567(3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)p...)
Affinity DataIC50:  3nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In DepthDetails US Patent