BDBM50223925 6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL398719

SMILES CN1CCN(Cc2ccc(Cc3cc4cnc(nc4n3C3CCCCC3)C#N)cc2)CC1

InChI Key InChIKey=OQXYQZMSUBLQAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223925   

TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223925(6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-cyc...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223925(6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-cyc...)
Affinity DataIC50:  730nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed