BDBM50226002 (R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoic acid::2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoic acid::3-(3-Pyridyl)-2-hydroxy-2-phosphonopropanoic acid::CHEMBL397829

SMILES OC(=O)C(O)(Cc1cccnc1)P(O)(O)=O

InChI Key InChIKey=FJVYPXVLXQXDHM-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50226002   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataKi:  9.75E+4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50:  2.54E+5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50:  2.54E+5nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50:  4.67E+5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed