BDBM50227669 (R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ureido)-2,3-dihydro-1H-inden-5-ylthio)-2-methylpropanoic acid::CHEMBL249865

SMILES CCN([C@@H]1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=AHHRDMWAAXCONK-QGZVFWFLSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227669   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227669((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227669((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene inductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227669((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at PPARdelta expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227669((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at PPARalpha expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed