BDBM50228409 8-(3-aminopiperidin-1-yl)-7-benzyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione::CHEMBL399216
SMILES Cn1c2nc(N3CCCC(N)C3)n(Cc3ccccc3)c2c(=O)n(C)c1=O
InChI Key InChIKey=BLGQZJNVPWQDPL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50228409
Affinity DataIC50: 82nMAssay Description:Inhibition of human DPP4 in Caco2 cells by fluorescene assayMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human recombinant DPP4 (39 to 766 residues) at 5 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant DPP4 (39 to 766 residues) using Ala-Pro-AFC as substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human recombinant DPP4 (39 to 766 residues) by surface plasmon resonance analysisMore data for this Ligand-Target Pair