BDBM50228418 CHEMBL393591::methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethylcarbamate

SMILES [#6]-[#8]-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=MQQUIUGJIRPZPV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50228418   

TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of mouse plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of rat plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Rattus norvegicus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  19.5nMAssay Description:Inhibition of rat uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(CHEMBL393591 | methyl 1-(diphenoxyphosphoryl)-2-(4...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of mouse thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed