BDBM50229085 (R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-2-methylbenzoyl)piperazin-1-yl)propan-1-one::CHEMBL251796

SMILES C[C@@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C

InChI Key InChIKey=CFVOAVDAPUQRNK-OAHLLOKOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229085   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229085((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...)
Affinity DataIC50:  1nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229085((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...)
Affinity DataIC50:  170nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229085((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229085((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...)
Affinity DataIC50:  700nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed