BDBM50229711 CHEMBL4074873
SMILES [H][C@@]12CN(C[C@]1([H])c1cnccc1N(C)C2=O)S(=O)(=O)c1ccc2occc2c1
InChI Key InChIKey=QODWZTUPLVMSQR-HZPDHXFCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50229711
Affinity DataEC50: 450nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Positive allosteric modulation of human glycine alpha3beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current respon...More data for this Ligand-Target Pair
Affinity DataEC50: 454nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as glycine-induced increase in current response a...More data for this Ligand-Target Pair
Affinity DataEC50: 327nMAssay Description:Positive allosteric modulation of human glycine alpha1 receptor expressed in HEK293T cells assessed as glycine-induced increase incurrent response af...More data for this Ligand-Target Pair
Affinity DataEC50: 327nMAssay Description:Positive allosteric modulation of human GlyRalpha1 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataEC50: 171nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium ...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium ...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1(Mus musculus)
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataEC50: 268nMAssay Description:Positive allosteric modulation of mouse GlyRalpha1 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-3(Mus musculus)
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataEC50: 490nMAssay Description:Positive allosteric modulation of mouse GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
Affinity DataEC50: 454nMAssay Description:Positive allosteric modulation of human GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataEC50: 171nMAssay Description:Positive allosteric modulation of human glycine alpha1beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current respon...More data for this Ligand-Target Pair