BDBM50230588 3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium; chloride::CHEMBL252441::CHEMBL402329

SMILES Cc1sc(CCO)c(C)[n+]1Cc1ccc(C)nc1N

InChI Key InChIKey=KRWSBNUXLKBCMX-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230588   

TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230588(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  28nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230588(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  56nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230588(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  25nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed