BDBM50230596 3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium; chloride::CHEMBL252842::CHEMBL256454

SMILES Cc1ccc(C[n+]2csc(CCO)c2)c(N)n1

InChI Key InChIKey=UDMDPXOJERMBDV-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230596   

TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230596(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  9.54E+3nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230596(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  9.50E+3nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230596(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  29nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed