BDBM50230828 5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide::CHEMBL257167::[5-(p-fluorophenyl)-2-ureido]thiophene-3-carboxamide

SMILES NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(F)cc1

InChI Key InChIKey=SAYGKHKXGCPTLX-UHFFFAOYSA-N

Data  1 KI  5 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230828   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50230828(5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide...)Copy SMILESCopy InChI

Affinity DataKd:  22nMAssay Description:Binding affinity to human JAK2More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVenus kinase receptor 2(Schistosoma mansoni)
Imperial College London

Curated by ChEMBL

LigandBDBM50230828(5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide...)Copy SMILESCopy InChI

Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Schistosoma mansoni N-terminal His6-tagged full-length VKR2 kinase domain expressed in baculovirus infected Sf9 insect cells in p...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI