BDBM50235508 CHEMBL254698::tert-butyl (R)-1-((R)-1,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-ylamino)-3-(2-fluorophenyl)-1-oxopropan-2-ylcarbamate

SMILES CN1C[C@@H](NC(=O)[C@@H](Cc2ccccc2F)NC(=O)OC(C)(C)C)C(=O)N(C)c2ccccc12

InChI Key InChIKey=BDTKEHDYWBVMLD-RTBURBONSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235508   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50235508(CHEMBL254698 | tert-butyl (R)-1-((R)-1,5-dimethyl-...)
Affinity DataIC50:  142nMAssay Description:Inhibition of human Nav1.7 sodium channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed