BDBM50236044 CHEMBL4066104
SMILES CNc1nc(Nc2ccc(C)c(NC(=O)C=C)c2)ncc1C(=O)Nc1cc(NC(=O)c2cc(OC)c(OC)c(OC)c2)ccc1C
InChI Key InChIKey=XURALSVDCFXBAX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50236044
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of full-length recombinant human GST-tagged p38alpha expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 265nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 1.02E+4nMAssay Description:Binding affinity to active state of full length fluorescent labeled human BMX (1 to 675 amino acid residues) expressed in bacterial expression system...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 437nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataEC50: 5.80nMAssay Description:Irreversible inhibition of inactive state of wild-type full-length recombinant His-tagged BMX phosphorylation (unknown origin) at tyrosine residue ex...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 81nMAssay Description:Binding affinity to inactive state of full length fluorescent labeled human BMX (1 to 675 amino acid residues) expressed in bacterial expression syst...More data for this Ligand-Target Pair