BDBM50238824 CHEMBL4064756
SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(NCCCN3CCOCC3)nc2n(CCc2ccc(NC(=O)C=C)cc2)c1=O
InChI Key InChIKey=FRJDZSFZHJQXRU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50238824
Affinity DataIC50: 12nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair