BDBM50240895 2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone::2-Imidazol-1-yl-1-(4-nitro-phenyl)-ethanone::CHEMBL162549

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Cn1ccnc1

InChI Key InChIKey=SBPGWXSTCFNGPY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50240895   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataKi:  1.05E+5nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataKi:  1.05E+5nMAssay Description:Inhibition of rat recombinant nNOS expressed in baculovirus-infected Sf9 cells assessed as conversion of oxyhemoglobin to methemoglobin by UV spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataKi: >5.00E+6nMAssay Description:Inhibition of C57BL/6 mouse eNOS assessed as conversion of oxyhemoglobin to methemoglobin by UV spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed