BDBM50240895 2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone::2-Imidazol-1-yl-1-(4-nitro-phenyl)-ethanone::CHEMBL162549
SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Cn1ccnc1
InChI Key InChIKey=SBPGWXSTCFNGPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50240895
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica
Curated by ChEMBL
Instituto De QuíMica MéDica
Curated by ChEMBL
Affinity DataKi: 1.05E+5nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+5nMAssay Description:Inhibition of rat recombinant nNOS expressed in baculovirus-infected Sf9 cells assessed as conversion of oxyhemoglobin to methemoglobin by UV spectro...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+6nMAssay Description:Inhibition of C57BL/6 mouse eNOS assessed as conversion of oxyhemoglobin to methemoglobin by UV spectrophotometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair