BDBM50240928 CHEMBL4067280
SMILES Cn1c2nc(S)n(CC(O)COc3ccc(Cl)cc3)c2c(=O)[nH]c1=O
InChI Key InChIKey=NZAKNENBMNKYOA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50240928
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Competitive inhibition of AEP (unknown origin) using varying levels of Z-AAN-AMC substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetCaspase-8(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 7.61E+4nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair