BDBM50241837 CHEMBL4102913::US10626113, Compound G::US10899756, Compound G

SMILES COc1ccc(CNc2c3CNCCc3nc3ccc(cc23)C#N)cc1Cl

InChI Key InChIKey=PMBQHJFQTGZRDS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241837   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant PDE5A1 using FAM-labelled cGMP as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed