BDBM50242157 CHEMBL4070894::US10626113, Compound B::US10899756, Compound B
SMILES COc1ccc(CNc2c3CN(C)CCc3nc3ccc(cc23)C#N)cc1Cl
InChI Key InChIKey=SZSQUMVPZIONEO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50242157
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Columbia University
Curated by ChEMBL
Columbia University
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Concentration required to inhibit the activity of K+ stimulated gastric ATPaseMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Columbia University
Curated by ChEMBL
Columbia University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Columbia University
Curated by ChEMBL
Columbia University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair