BDBM50243266 (2R,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL520736

SMILES CN[C@H]1C[C@H](Oc2ccccc2C)c2ccccc2C1

InChI Key InChIKey=FDBFTQAPQQWDDD-QAPCUYQASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243266   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243266((2R,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243266((2R,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243266((2R,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed