BDBM50243844 1-(3-Chloro-phenyl)-3-[1-(3,3-dimethyl-butyl)-4-phenyl-piperidin-4-ylmethyl]-urea::1-(3-chlorophenyl)-3-((1-(3,3-dimethylbutyl)-4-phenylpiperidin-4-yl)methyl)urea::CHEMBL488294

SMILES CC(C)(C)CCN1CCC(CNC(=O)Nc2cccc(Cl)c2)(CC1)c1ccccc1

InChI Key InChIKey=PKQRYUSYILGVOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243844   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243844(1-(3-Chloro-phenyl)-3-[1-(3,3-dimethyl-butyl)-4-ph...)
Affinity DataIC50:  88nMAssay Description:Antagonist activity at human ERG by voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243844(1-(3-Chloro-phenyl)-3-[1-(3,3-dimethyl-butyl)-4-ph...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243844(1-(3-Chloro-phenyl)-3-[1-(3,3-dimethyl-butyl)-4-ph...)
Affinity DataIC50:  245nMAssay Description:Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed