BDBM50243929 4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL488645

SMILES COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1cn(COC(C)C)c2ccccc12

InChI Key InChIKey=CPWSAJBBZKPYRF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50243929   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed