BDBM50244022 CHEMBL449192::N-[1-(4'-Acetylamino-biphenyl-4-yl)-2-morpholin-4-yl-ethyl]-2-(6,7-dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-N-methyl-acetamide

SMILES CN(C(CN1CCOCC1)c1ccc(cc1)-c1ccc(NC(C)=O)cc1)C(=O)CN1C(=O)COc2cc(C)c(C)cc12

InChI Key InChIKey=BEKQKLIWZQJREN-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244022   

TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50244022(CHEMBL449192 | N-[1-(4'-Acetylamino-biphenyl-4-yl)...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50244022(CHEMBL449192 | N-[1-(4'-Acetylamino-biphenyl-4-yl)...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50244022(CHEMBL449192 | N-[1-(4'-Acetylamino-biphenyl-4-yl)...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50244022(CHEMBL449192 | N-[1-(4'-Acetylamino-biphenyl-4-yl)...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed