BDBM50244228 CHEMBL458319::cyclopropylmethyl 7-chloro-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate

SMILES Cn1c2c(ncn2c2ccc(Cl)cc2c1=O)C(=O)OCC1CC1

InChI Key InChIKey=JKCPXTTYNRGYQQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244228   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244228(CHEMBL458319 | cyclopropylmethyl 7-chloro-4-methyl...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244228(CHEMBL458319 | cyclopropylmethyl 7-chloro-4-methyl...)
Affinity DataKi:  16.4nMAssay Description:Binding affinity to GABAA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed