BDBM50244262 CHEMBL471978::ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate
SMILES CCOC(=O)c1ncn2c1n(C)c(=O)c1cc(ccc21)C#C
InChI Key InChIKey=QOICRVBHAUSMFA-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50244262
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 1.68nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 21.4nMAssay Description:Binding affinity to GABAA alpha-2-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 28.4nMAssay Description:Binding affinity to GABAA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: >100nMAssay Description:Binding affinity to GABAA alpha-6-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 198nMAssay Description:Binding affinity to GABAA alpha-3-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair