BDBM50244263 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazolin-3-yl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate::CHEMBL394710

SMILES Cn1c2c(ncn2c2ccc(cc2c1=O)C#C)C(=O)OCCOC(=O)c1ncn2c1n(C)c(=O)c1cc(ccc21)C#C

InChI Key InChIKey=HQCFOKBDGJUVDT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244263   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244263(7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]...)
Affinity DataKi:  15nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244263(7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]...)
Affinity DataKi: >1.50E+3nMAssay Description:Binding affinity to GABAA alpha-4-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244263(7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]...)
Affinity DataKi: >1.50E+3nMAssay Description:Binding affinity to GABAA alpha-6-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed