BDBM50244295 (-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol::CHEMBL471994::cis-(+)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol

SMILES Cc1ccccc1C1CCN(C[C@H]2CCc3cccnc3[C@@H](O)C2)CC1

InChI Key InChIKey=RWZHKEZRFILBTQ-AVRDEDQJSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244295   

TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)
Affinity DataIC50:  310nMAssay Description:Displacement of [35S]MK499 from human ERG K+ channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)
Affinity DataIC50:  310nMAssay Description:Displacement of [35S]MK499 from human ERG K+ channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed