BDBM50244313 1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]methyl}-3H-spiro[2-benzofuran-1,4'-piperidine]::CHEMBL471299

SMILES Cc1nn(cc1CN1CCC2(CC1)OCc1ccccc21)-c1c(Cl)cccc1NS(C)(=O)=O

InChI Key InChIKey=JWHOPIWZAFADGZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244313   

TargetMu-type opioid receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244313(1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244313(1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244313(1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [35S]MK499 from human ERG in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed