BDBM50245547 4-(4-(2-Chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihydropyrrolo[3,4-c]carbazol-6(1H )-yl)butanenitrile::4-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihydropyrrolo[3,4-c]carbazol-6(1H)-yl)butanenitrile::CHEMBL520240
SMILES Oc1ccc2n(CCCC#N)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl
InChI Key InChIKey=QHQBMNXWJUAAHX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50245547
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair