BDBM50245731 6-[3-(Dimethylamino)propyl]-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H )-dione::CHEMBL508515

SMILES CN(C)CCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1

InChI Key InChIKey=PQYWWLYGKICJKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245731   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245731(6-[3-(Dimethylamino)propyl]-9-hydroxy-4-phenylpyrr...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245731(6-[3-(Dimethylamino)propyl]-9-hydroxy-4-phenylpyrr...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245731(6-[3-(Dimethylamino)propyl]-9-hydroxy-4-phenylpyrr...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed