BDBM50246456 4-(2-(3,4-dihydro-2H-chromen-3-yl)-3H-benzo[d]imidazol-5-yl)pyrimidin-2-amine::4-(2-(chroman-3-yl)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine::CHEMBL454654

SMILES Nc1nccc(n1)-c1ccc2[nH]c(nc2c1)C1COc2ccccc2C1

InChI Key InChIKey=WHRSQWOTNWLODD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246456   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50246456(4-(2-(3,4-dihydro-2H-chromen-3-yl)-3H-benzo[d]imid...)
Affinity DataIC50:  66nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50246456(4-(2-(3,4-dihydro-2H-chromen-3-yl)-3H-benzo[d]imid...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed