BDBM50246541 (R)-3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2-(1-methoxypropan-2-yloxy)pyridin-3-yl)-2-(2-methoxyethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL514435
SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(O[C@H](C)COC)c(c1)-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1
InChI Key InChIKey=ZAFPETYWHMLHGN-QGZVFWFLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50246541
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Canis familiaris)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 734nMAssay Description:Inhibition of canine retina PDE6 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair