BDBM50247033 2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic acid::CHEMBL460496

SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O

InChI Key InChIKey=DFGNDJBYANKHIO-UHFFFAOYSA-N

Data  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50247033   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  2.31E+5nMAssay Description:Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  4.21E+4nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to recombinant human N-terminal GST-tagged HSP90-CTD by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  4.21E+4nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247033(2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...)
Affinity DataIC50:  2.31E+5nMAssay Description:Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed