BDBM50248119 CHEMBL462161::N2-(4-(benzo[d]thiazol-2-yl)phenyl)-N4,N4-dimethylpyrimidine-2,4-diamine

SMILES CN(C)c1ccnc(Nc2ccc(cc2)-c2nc3ccccc3s2)n1

InChI Key InChIKey=UTQLMOIUFSXMLI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248119   

TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248119(CHEMBL462161 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248119(CHEMBL462161 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248119(CHEMBL462161 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248119(CHEMBL462161 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248119(CHEMBL462161 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed