BDBM50248524 3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N-hydroxyacrylamide::CHEMBL523601::US10201527, Compound 56::US10736881, Compound 56::US8551988, 56

SMILES ONC(=O)\C=C\c1ccc2n(CCCn3ccnc3)c(CCc3ccccc3)nc2c1

InChI Key InChIKey=KLDUYMMXGOVQBM-FMIVXFBMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248524   

TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248524(3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-b...)
Affinity DataIC50:  158nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248524(3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-b...)
Affinity DataIC50:  158nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248524(3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-b...)
Affinity DataIC50:  158nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248524(3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-b...)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed