BDBM50248573 CHEMBL464719::N-hydroxy-3-(2-phenethyl-1-(3,4,5-trimethoxybenzyl)-1H-benzo[d]imidazol-5-yl)propanamide::US10201527, Compound 45::US10736881, Compound 45

SMILES COc1cc(Cn2c(CCc3ccccc3)nc3cc(CCC(=O)NO)ccc23)cc(OC)c1OC

InChI Key InChIKey=PUOYVRKIQWZKMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248573   

TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248573(CHEMBL464719 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248573(CHEMBL464719 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  167nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248573(CHEMBL464719 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  167nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent