BDBM50248889 8-(2,4-Difluoro-phenylamino)-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one::CHEMBL474177

SMILES Fc1ccc(Nc2ccc3c(c2)ccc2ncccc2c3=O)c(F)c1

InChI Key InChIKey=VSQHEDJSDFTDQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248889   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50248889(8-(2,4-Difluoro-phenylamino)-benzo[4,5]cyclohepta[...)
Affinity DataIC50:  330nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed