BDBM50249531 CHEMBL4081426

SMILES CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC(C)C)ccc12

InChI Key InChIKey=UZLLGNWABVRSKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249531   

TargetEndothelin receptor type B(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50249531(CHEMBL4081426)
Affinity DataIC50:  698nMAssay Description:Antagonist activity at ETB receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50249531(CHEMBL4081426)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at ETA receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed