BDBM50250586 CHEMBL4093140

SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)CN[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

InChI Key InChIKey=RDCIPOBDQMOUKD-LXJGJVCSSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50250586   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.0100nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  1nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50:  0.0100nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed