BDBM50250803 CHEMBL4083252
SMILES COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1
InChI Key InChIKey=RRTCFJGKAMKAIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50250803
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-Way100635 from recombinant human 5HT1A receptor transiently expressed in CHO cell membranes measured after 90 mins by microbeta ...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]N-methylspiperone from D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting method relative to...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [125I]IABN from recombinant human D3 receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]-pyrilamine from recombinant human H1 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta scintil...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT2B receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [3H]-prazosin from recombinant human alpha1A adrenergic receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]-prazosin from recombinant human alpha1B adrenergic receptor transiently expressed in HEKT cells measured after 90 mins by microb...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 128nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT7A receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta scintillati...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 159nMAssay Description:Displacement of [3H]-mesulergine from recombinant human 5HT2C receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbe...More data for this Ligand-Target Pair
Affinity DataKi: 221nMAssay Description:Displacement of [3H]-rauwolscine from recombinant human alpha2A adrenergic receptor stably expressed in MDCK cells measured after 90 mins by microbet...More data for this Ligand-Target Pair
Affinity DataKi: 241nMAssay Description:Displacement of [3H]-rauwolscine from recombinant human alpha2B adrenergic receptor transiently expressed in HEKT cells measured after 90 mins by mic...More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [125I]IABN from recombinant human D2 long receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 433nMAssay Description:Displacement of [3H]-rauwolscine from recombinant human alpha2C adrenergic receptor stably expressed in MDCK cells measured after 90 mins by microbet...More data for this Ligand-Target Pair
Affinity DataKi: 577nMAssay Description:Displacement of [3H]N-methylspiperone from recombinant human D2 receptor stably expressed in fibroblast measured after 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
Affinity DataKi: 721nMAssay Description:Displacement of [3H]N-methylspiperone from recombinant human D4 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta s...More data for this Ligand-Target Pair
Affinity DataKi: 871nMAssay Description:Displacement of [125I]-Iodo-aminopotentidine from human histamine H2 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 1.42E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 2.03E+3nMAssay Description:Displacement of [3H]-5-CT from recombinant human 5HT1B receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta scintillat...More data for this Ligand-Target Pair
Affinity DataKi: 3.02E+3nMAssay Description:Displacement of [3H]-SCH23390 from recombinant human D5 receptor transiently expressed in HEK cell membranes measured after 90 mins by microbeta scin...More data for this Ligand-Target Pair
Affinity DataEC50: 254nMAssay Description:Agonist activity at recombinant human D2 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 359nMAssay Description:Agonist activity at recombinant human D4 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 328nMAssay Description:Antagonist activity at recombinant human D2 receptor expressed in CHOK1 cells assessed as inhibition of quinpirole-induced beta arrestin2 recruitment...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at recombinant human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta arrestin2 recruitment p...More data for this Ligand-Target Pair
Affinity DataEC50: 167nMAssay Description:Agonist activity at recombinant human D3 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins...More data for this Ligand-Target Pair