BDBM50252380 CHEMBL4068283

SMILES CCc1ccc(Nc2nc3cc(N)ccc3o2)cc1

InChI Key InChIKey=HMUSVHZYELITJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252380   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50252380(CHEMBL4068283)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of STAT3 in human K562 cells assessed as reduction in STAT3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-6(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50252380(CHEMBL4068283)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed