BDBM50252431 CHEMBL4070869

SMILES CC(C)CN1CC(=Cc2cc(ccc2C1=O)-c1ccc(C)cc1)C(=O)Nc1ccc(CN(C)C2CCOCC2)cc1

InChI Key InChIKey=QWKBLVGDYWYJNQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252431   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)
Affinity DataIC50:  387nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 expressed in human U2OS cells after 120 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)
Affinity DataIC50:  140nMAssay Description:Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH P450 reductase using 7-ethoxyresorufin as substrate in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed