BDBM50252431 CHEMBL4070869
SMILES CC(C)CN1CC(=Cc2cc(ccc2C1=O)-c1ccc(C)cc1)C(=O)Nc1ccc(CN(C)C2CCOCC2)cc1
InChI Key InChIKey=QWKBLVGDYWYJNQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50252431
Affinity DataIC50: 387nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 expressed in human U2OS cells after 120 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH P450 reductase using 7-ethoxyresorufin as substrate in pre...More data for this Ligand-Target Pair
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair