BDBM50252582 (2-(4-(methylthio)benzyl)phenyl)-N,N-dimethylmethanamine::CHEMBL492842

SMILES CSc1ccc(Cc2ccccc2CN(C)C)cc1

InChI Key InChIKey=QBOITYXCKDGUNE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252582   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252582((2-(4-(methylthio)benzyl)phenyl)-N,N-dimethylmetha...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252582((2-(4-(methylthio)benzyl)phenyl)-N,N-dimethylmetha...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252582((2-(4-(methylthio)benzyl)phenyl)-N,N-dimethylmetha...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed