BDBM50252779 CHEMBL494469::N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morpholinyl)-6-phthalazinyl)benzamide

SMILES C[C@H]1COCCN1c1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=OYVCLLCTQUHVCE-INIZCTEOSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252779   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  4.83E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed