BDBM50252874 CHEMBL494265::Methyl 4-(spiro[chromene-2,4'-piperidine]-4-yl)benzoate

SMILES COC(=O)c1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key InChIKey=PZYPBUIOQZWSRY-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252874   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252874(CHEMBL494265 | Methyl 4-(spiro[chromene-2,4'-piper...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252874(CHEMBL494265 | Methyl 4-(spiro[chromene-2,4'-piper...)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252874(CHEMBL494265 | Methyl 4-(spiro[chromene-2,4'-piper...)
Affinity DataIC50:  663nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50252874(CHEMBL494265 | Methyl 4-(spiro[chromene-2,4'-piper...)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed