BDBM50253419 CHEMBL448274::Naphthalen-1-ylmethyl-{2-[(naphthalen-1-ylmethyl)-amino]-6-phenethyl-pyrimidin-4-yl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N(Cc1cccc2ccccc12)c1cc(CCc2ccccc2)nc(NCc2cccc3ccccc23)n1

InChI Key InChIKey=SFXSWCIBDKUWNA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253419   

TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253419(CHEMBL448274 | Naphthalen-1-ylmethyl-{2-[(naphthal...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253419(CHEMBL448274 | Naphthalen-1-ylmethyl-{2-[(naphthal...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to ERbeta (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253419(CHEMBL448274 | Naphthalen-1-ylmethyl-{2-[(naphthal...)
Affinity DataIC50: >1.00E+6nMAssay Description:Antagonist activity at ERalpha in human HEC1 cells assessed as inhibition of estrogen-induced transcriptional activity after 24 hrs by reporter gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed